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Semisynthetic Viral Inhibitor for Light Control of the MHC I Peptide Loading Complex

The immune system detects virally or malignantly transformed cells via peptide‐loaded major histocompatibility complex class I (pMHC I) molecules on the cell surface. MHC I molecules are loaded with cargo peptides in the endoplasmic reticulum (ER) by the highly dynamic multiprotein peptide loading c...

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Detalles Bibliográficos
Autores principales: Winter, Christian, Domnick, Alexander, Cernova, Darja, Tampé, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092072/
https://www.ncbi.nlm.nih.gov/pubmed/36121731
http://dx.doi.org/10.1002/anie.202211826