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Quantitative impact of pre‐analytical process on plasma uracil when testing for dihydropyrimidine dehydrogenase deficiency

AIMS: Determining dihydropyrimidine dehydrogenase (DPD) activity by measuring patient's uracil (U) plasma concentration is mandatory before fluoropyrimidine (FP) administration in France. In this study, we aimed to refine the pre‐analytical recommendations for determining U and dihydrouracil (U...

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Detalles Bibliográficos
Autores principales: Maillard, Maud, Launay, Manon, Royer, Bernard, Guitton, Jérôme, Gautier‐Veyret, Elodie, Broutin, Sophie, Tron, Camille, Le Louedec, Félicien, Ciccolini, Joseph, Richard, Damien, Alarcan, Hugo, Haufroid, Vincent, Tafzi, Naïma, Schmitt, Antonin, Etienne‐Grimaldi, Marie‐Christine, Narjoz, Céline, Thomas, Fabienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092089/
https://www.ncbi.nlm.nih.gov/pubmed/36104927
http://dx.doi.org/10.1111/bcp.15536