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Cell‐intrinsic melanin fails to protect melanocytes from ultraviolet‐mutagenesis in the absence of epidermal melanin

Melanin is a free‐radical scavenger, antioxidant, and broadband absorber of ultraviolet (UV) radiation which protects the skin from environmental carcinogenesis. However, melanin synthesis and UV‐induced reactive melanin species are also implicated in melanocyte genotoxicity. Here, we attempted to r...

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Detalles Bibliográficos
Autores principales: Weiss, Tirzah J., Crawford, Emma R., Posada, Valentina, Rahman, Hafeez, Liu, Tong, Murphy, Brandon M., Arnold, Tiffany E., Gray, Shannon, Hu, Zhexuan, Hennessey, Rebecca C., Yu, Lianbo, D'Orazio, John A., Burd, Craig J., Zippin, Jonathan H., Grossman, Douglas, Burd, Christin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092168/
https://www.ncbi.nlm.nih.gov/pubmed/36148789
http://dx.doi.org/10.1111/pcmr.13070