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Cell‐intrinsic melanin fails to protect melanocytes from ultraviolet‐mutagenesis in the absence of epidermal melanin
Melanin is a free‐radical scavenger, antioxidant, and broadband absorber of ultraviolet (UV) radiation which protects the skin from environmental carcinogenesis. However, melanin synthesis and UV‐induced reactive melanin species are also implicated in melanocyte genotoxicity. Here, we attempted to r...
Autores principales: | Weiss, Tirzah J., Crawford, Emma R., Posada, Valentina, Rahman, Hafeez, Liu, Tong, Murphy, Brandon M., Arnold, Tiffany E., Gray, Shannon, Hu, Zhexuan, Hennessey, Rebecca C., Yu, Lianbo, D'Orazio, John A., Burd, Craig J., Zippin, Jonathan H., Grossman, Douglas, Burd, Christin E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092168/ https://www.ncbi.nlm.nih.gov/pubmed/36148789 http://dx.doi.org/10.1111/pcmr.13070 |
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