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Effect of the human endotoxin challenge on tedizolid tissue penetration

The effects of the human endotoxin challenge on tissue pharmacokinetics are unknown. In the present study, we aimed to assess the effect of the endotoxin challenge on interstitial fluid pharmacokinetics of tedizolid in healthy volunteers using intramuscular microdialysis. Eight healthy male subjects...

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Detalles Bibliográficos
Autores principales: Jorda, Anselm, Wulkersdorfer, Beatrix, Schoergenhofer, Christian, Matzneller, Peter, al Jalali, Valentin, Bauer, Martin, Wölfl‐Duchek, Michael, Lackner, Edith, Dorn, Christoph, Jilma, Bernd, Zeitlinger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092186/
https://www.ncbi.nlm.nih.gov/pubmed/36223278
http://dx.doi.org/10.1111/bcp.15564