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Contribution of animal models to the mechanistic understanding of Alternative Pathway and Amplification Loop (AP/AL)‐driven Complement‐mediated Diseases

This review aimed to capture the key findings that animal models have provided around the role of the alternative pathway and amplification loop (AP/AL) in disease. Animal models, particularly mouse models, have been incredibly useful to define the role of complement and the alternative pathway in h...

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Detalles Bibliográficos
Autores principales: Gibson, Beth G., Cox, Thomas E., Marchbank, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092198/
https://www.ncbi.nlm.nih.gov/pubmed/36203396
http://dx.doi.org/10.1111/imr.13141