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Per‐ and polyfluoroalkyl substances activate UPR pathway, induce steatosis and fibrosis in liver cells

Per‐ and polyfluoroalkyl substances (PFAS), which include perfluorooctanoic acid (PFOA), heptafluorobutyric acid (HFBA), and perfluorotetradecanoic acid (PFTA), are commonly occurring organic pollutants. Exposure to PFAS affects the immune system, thyroid and kidney function, lipid metabolism, and i...

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Detalles Bibliográficos
Autores principales: Qi, Qi, Niture, Suryakant, Gadi, Sashi, Arthur, Elena, Moore, John, Levine, Keith E., Kumar, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092267/
https://www.ncbi.nlm.nih.gov/pubmed/36251517
http://dx.doi.org/10.1002/tox.23680