Inhibition of canalicular and sinusoidal taurocholate efflux by cholestatic drugs in human hepatoma HepaRG cells

HepaRG cells are highly‐differentiated human hepatoma cells, which are increasingly recognized as a convenient cellular model for in vitro evaluation of hepatic metabolism, transport, and/or toxicity of drugs. The present study was designed to evaluate whether HepaRG cells can also be useful for stu...

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Detalles Bibliográficos
Autores principales: Le Vée, Marc, Moreau, Amélie, Jouan, Elodie, Denizot, Claire, Parmentier, Yannick, Fardel, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092305/
https://www.ncbi.nlm.nih.gov/pubmed/36195987
http://dx.doi.org/10.1002/bdd.2333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092305/
https://www.ncbi.nlm.nih.gov/pubmed/36195987
http://dx.doi.org/10.1002/bdd.2333

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