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Inhibition of canalicular and sinusoidal taurocholate efflux by cholestatic drugs in human hepatoma HepaRG cells
HepaRG cells are highly‐differentiated human hepatoma cells, which are increasingly recognized as a convenient cellular model for in vitro evaluation of hepatic metabolism, transport, and/or toxicity of drugs. The present study was designed to evaluate whether HepaRG cells can also be useful for stu...
Autores principales: | Le Vée, Marc, Moreau, Amélie, Jouan, Elodie, Denizot, Claire, Parmentier, Yannick, Fardel, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092305/ https://www.ncbi.nlm.nih.gov/pubmed/36195987 http://dx.doi.org/10.1002/bdd.2333 |
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