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P2X7 receptor activation impairs antitumour activity of natural killer cells

BACKGROUND AND PURPOSE: A high number of intratumoural infiltrating natural killer (NK) cells is associated with better survival in several types of cancer, constituting an important first line of defence against tumours. Hypoxia in the core of solid tumours induces cellular stress and ATP release i...

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Detalles Bibliográficos
Autores principales: Baroja‐Mazo, Alberto, Peñín‐Franch, Alejandro, Lucas‐Ruiz, Fernando, de Torre‐Minguela, Carlos, Alarcón‐Vila, Cristina, Hernández‐Caselles, Trinidad, Pelegrín, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092446/
https://www.ncbi.nlm.nih.gov/pubmed/36098250
http://dx.doi.org/10.1111/bph.15951