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Sialic Acid 4‐N‐Piperazine and Piperidine Derivatives Bind with High Affinity to the P. mirabilis Sialic Acid Sodium Solute Symporter

In search for novel antibacterial compounds, bacterial sialic acid uptake inhibition represents a promising strategy. Sialic acid plays a critical role for growth and colonisation of several pathogenic bacteria, and its uptake inhibition in bacteria was recently demonstrated to be a viable strategy...

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Detalles Bibliográficos
Autores principales: Bozzola, Tiago, Johnsson, Richard E., Nilsson, Ulf J., Ellervik, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092485/
https://www.ncbi.nlm.nih.gov/pubmed/36121381
http://dx.doi.org/10.1002/cmdc.202200351