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Genetic variation in NFE2L2 is associated with outcome following aneurysmal subarachnoid haemorrhage

BACKGROUND AND PURPOSE: Nuclear factor erythroid 2‐related factor 2 (NRF2; encoded by the NFE2L2 gene) has been implicated in outcome following aneurysmal subarachnoid haemorrhage (aSAH) through its activity as a regulator of inflammation, oxidative injury and blood breakdown product clearance. The...

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Detalles Bibliográficos
Autores principales: Gaastra, Ben, Duncan, Poppy, Bakker, Mark K., Hostettler, Isabel C., Alg, Varinder S., Houlden, Henry, Ruigrok, Ynte M., Galea, Ian, Tapper, Will, Werring, David, Bulters, Diederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092511/
https://www.ncbi.nlm.nih.gov/pubmed/36148820
http://dx.doi.org/10.1111/ene.15571