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Unveiling the Potential of Innovative Gold(I) and Silver(I) Selenourea Complexes as Anticancer Agents Targeting TrxR and Cellular Redox Homeostasis

A series of NHC‐based selenourea Ag(I) and Au(I) complexes were evaluated for their anticancer potential in vitro, on 2D and 3D human cancer cell systems. All NHC‐based selenourea complexes possess an outstanding cytotoxic potency, which was comparable or even better than that of the reference metal...

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Detalles Bibliográficos
Autores principales: De Franco, Michele, Saab, Marina, Porchia, Marina, Marzano, Cristina, Nolan, Steven P., Nahra, Fady, Van Hecke, Kristof, Gandin, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092581/
https://www.ncbi.nlm.nih.gov/pubmed/36106679
http://dx.doi.org/10.1002/chem.202201898