Loss of HRD functional phenotype impedes immunotherapy and can be reversed by HDAC inhibitor in ovarian cancer

In recent years, homologous recombination deficiency (HRD) has not achieved the expected substantial promotion of immunotherapeutic efficacy in ovarian cancer. This study aims to explore the role of HRD functional phenotype as a powerful biomarker in identifying HRD patients who may benefit from imm...

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Detalles Bibliográficos
Autores principales: Yang, Dong, Huang, Fu-Xue, Wei, Wei, Li, Qia-Qia, Wu, Jun-Wan, Huang, Yun, Li, Zhi-Ling, Zhang, Hai-Liang, Li, Xuan, Yuan, Qiu-Er, Chen, Qing-shan, Feng, Gong-kan, Rong, Deng, Li, Jun-Dong, Zhu, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092773/
https://www.ncbi.nlm.nih.gov/pubmed/37063431
http://dx.doi.org/10.7150/ijbs.79654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092773/
https://www.ncbi.nlm.nih.gov/pubmed/37063431
http://dx.doi.org/10.7150/ijbs.79654

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