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Edaravone Administered Orally and Via Nasogastric Tube in Healthy Adults: A Comparative Bioavailability Phase 1 Study

Intravenous edaravone is used to treat patients with amyotrophic lateral sclerosis. This randomized, open‐label, two‐way crossover, single‐dose phase 1 study compared the relative bioavailability of a newly developed edaravone oral suspension when administered orally and via a nasogastric tube (NGT)...

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Detalles Bibliográficos
Autores principales: Shimizu, Hidetoshi, Nishimura, Yukiko, Shiide, Youichi, Ueda, Masaki, Yokota, Shoko, Kato, Yuichiro, Hirai, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092809/
https://www.ncbi.nlm.nih.gov/pubmed/36225132
http://dx.doi.org/10.1002/cpdd.1175