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Edaravone Administered Orally and Via Nasogastric Tube in Healthy Adults: A Comparative Bioavailability Phase 1 Study
Intravenous edaravone is used to treat patients with amyotrophic lateral sclerosis. This randomized, open‐label, two‐way crossover, single‐dose phase 1 study compared the relative bioavailability of a newly developed edaravone oral suspension when administered orally and via a nasogastric tube (NGT)...
Autores principales: | Shimizu, Hidetoshi, Nishimura, Yukiko, Shiide, Youichi, Ueda, Masaki, Yokota, Shoko, Kato, Yuichiro, Hirai, Manabu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092809/ https://www.ncbi.nlm.nih.gov/pubmed/36225132 http://dx.doi.org/10.1002/cpdd.1175 |
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