Rapid multi‐attribute characterization of intact bispecific antibodies by a microfluidic chip‐based integrated icIEF‐MS technology

Rapid, direct identification and quantitation of protein charge variants, and assessment of critical quality attributes with high sensitivity are important drivers required to accelerate the development of biotherapeutics. We describe the use of an enhanced microfluidic chip‐based integrated imaged...

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Detalles Bibliográficos
Autores principales: Ostrowski, Maggie A., Mack, Scott, Ninonuevo, Milady, Yan, John, ElNaggar, Mariam, Gentalen, Erik, Michels, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Taster: Ms Detection in Liquid Phase Separations 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092839/
https://www.ncbi.nlm.nih.gov/pubmed/36200174
http://dx.doi.org/10.1002/elps.202200165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092839/
https://www.ncbi.nlm.nih.gov/pubmed/36200174
http://dx.doi.org/10.1002/elps.202200165

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