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Rapid multi‐attribute characterization of intact bispecific antibodies by a microfluidic chip‐based integrated icIEF‐MS technology
Rapid, direct identification and quantitation of protein charge variants, and assessment of critical quality attributes with high sensitivity are important drivers required to accelerate the development of biotherapeutics. We describe the use of an enhanced microfluidic chip‐based integrated imaged...
Autores principales: | Ostrowski, Maggie A., Mack, Scott, Ninonuevo, Milady, Yan, John, ElNaggar, Mariam, Gentalen, Erik, Michels, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092839/ https://www.ncbi.nlm.nih.gov/pubmed/36200174 http://dx.doi.org/10.1002/elps.202200165 |
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