Passaging Primary Human Bronchial Epithelia Reduces CFTR-Mediated Fluid Transport and Alters mRNA Expression

Primary human bronchial epithelial cultures (HBECs) are used to study airway physiology, disease, and drug development. HBECs often replicate human airway physiology/pathophysiology. Indeed, in the search for cystic fibrosis (CF) transmembrane conductance regulator (CFTR) therapies, HBECs were seen...

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Detalles Bibliográficos
Autores principales: Wu, Tongde, Wrennall, Joe A., Dang, Hong, Baines, Deborah L., Tarran, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092965/
https://www.ncbi.nlm.nih.gov/pubmed/37048070
http://dx.doi.org/10.3390/cells12070997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092965/
https://www.ncbi.nlm.nih.gov/pubmed/37048070
http://dx.doi.org/10.3390/cells12070997

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