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Early Alterations of RNA Binding Protein (RBP) Homeostasis and ER Stress-Mediated Autophagy Contributes to Progressive Retinal Degeneration in the rd10 Mouse Model of Retinitis Pigmentosa (RP)

The retinal degeneration 10 (rd10) mouse model is widely used to study retinitis pigmentosa (RP) pathomechanisms. It offers a rather unique opportunity to study trans-neuronal degeneration because the cell populations in question are separated anatomically and the mutated Pde6b gene is selectively e...

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Detalles Bibliográficos
Autores principales: Yamoah, Alfred, Tripathi, Priyanka, Guo, Haihong, Scheve, Leonie, Walter, Peter, Johnen, Sandra, Müller, Frank, Weis, Joachim, Goswami, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092976/
https://www.ncbi.nlm.nih.gov/pubmed/37048167
http://dx.doi.org/10.3390/cells12071094