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Evaluating Focal Areas of Signal Intensity (FASI) in Children with Neurofibromatosis Type-1 (NF1) Treated with Selumetinib on Pediatric Brain Tumor Consortium (PBTC)-029B

SIMPLE SUMMARY: Focal areas of signal intensity (FASI) are common neuro-imaging abnormalities in children with neurofibromatosis type 1 (NF1). They may confound tumor evaluations and have been associated with neurocognitive differences in some studies. Selumetinib is a MEK inhibitor recently studied...

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Detalles Bibliográficos
Autores principales: Pillay-Smiley, Natasha, Leach, James, Lane, Adam, Hummel, Trent, Fangusaro, Jason, de Blank, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092996/
https://www.ncbi.nlm.nih.gov/pubmed/37046770
http://dx.doi.org/10.3390/cancers15072109