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Increased Local Testosterone Levels Alter Human Fallopian Tube mRNA Profile and Signaling

SIMPLE SUMMARY: Increased testosterone has been associated with increased risk of ovarian cancer. High Grade Serous Ovarian Carcinoma (HGSOC) mostly originates from the fallopian tube epithelium (FTE), however, the stepwise events that occur during its tumorigenic transformation are unknown. Early l...

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Detalles Bibliográficos
Autores principales: Russo, Angela, Cain, Brian P., Jackson-Bey, Tia, Lopez Carrero, Alfredo, Miglo, Jane, MacLaughlan, Shannon, Isenberg, Brett C., Coppeta, Jonathan, Burdette, Joanna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093055/
https://www.ncbi.nlm.nih.gov/pubmed/37046723
http://dx.doi.org/10.3390/cancers15072062