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Tau Transfer via Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System

Tauopathies are neurodegenerative disorders involving the accumulation of tau isoforms in cell subpopulations such as astrocytes. The origins of the 3R and 4R isoforms of tau that accumulate in astrocytes remain unclear. Extracellular vesicles (EVs) were isolated from primary neurons overexpressing...

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Detalles Bibliográficos
Autores principales: Perbet, Romain, Zufferey, Valentin, Leroux, Elodie, Parietti, Enea, Espourteille, Jeanne, Culebras, Lucas, Perriot, Sylvain, Du Pasquier, Renaud, Bégard, Séverine, Deramecourt, Vincent, Déglon, Nicole, Toni, Nicolas, Buée, Luc, Colin, Morvane, Richetin, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093208/
https://www.ncbi.nlm.nih.gov/pubmed/37048058
http://dx.doi.org/10.3390/cells12070985