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Effect of the Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulator Dipraglurant on Motor and Non-Motor Symptoms of Parkinson’s Disease

Parkinson’s disease (PD) patients suffer not only from the primary motor symptoms of the disease but also from a range of non-motor symptoms (NMS) that cause disability and low quality of life. Excessive glutamate activity in the basal ganglia resulting from degeneration of the nigrostriatal dopamin...

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Detalles Bibliográficos
Autores principales: Epping-Jordan, Mark P., Girard, Françoise, Bessis, Anne-Sophie, Mutel, Vincent, Boléa, Christelle, Derouet, Francis, Bessif, Abdelhak, Mingard, Brice, Barbier, Stéphanie, Paradis, Justine S., Rocher, Jean-Philippe, Lütjens, Robert, Kalinichev, Mikhail, Poli, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093229/
https://www.ncbi.nlm.nih.gov/pubmed/37048075
http://dx.doi.org/10.3390/cells12071004