Cargando…
Effect of the Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulator Dipraglurant on Motor and Non-Motor Symptoms of Parkinson’s Disease
Parkinson’s disease (PD) patients suffer not only from the primary motor symptoms of the disease but also from a range of non-motor symptoms (NMS) that cause disability and low quality of life. Excessive glutamate activity in the basal ganglia resulting from degeneration of the nigrostriatal dopamin...
Autores principales: | Epping-Jordan, Mark P., Girard, Françoise, Bessis, Anne-Sophie, Mutel, Vincent, Boléa, Christelle, Derouet, Francis, Bessif, Abdelhak, Mingard, Brice, Barbier, Stéphanie, Paradis, Justine S., Rocher, Jean-Philippe, Lütjens, Robert, Kalinichev, Mikhail, Poli, Sonia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093229/ https://www.ncbi.nlm.nih.gov/pubmed/37048075 http://dx.doi.org/10.3390/cells12071004 |
Ejemplares similares
-
Allosteric Molecular Switches in Metabotropic Glutamate Receptors
por: Orgován, Zoltán, et al.
Publicado: (2020) -
Conformational fingerprinting of allosteric modulators in metabotropic glutamate receptor 2
por: Liauw, Brandon Wey-Hung, et al.
Publicado: (2022) -
Allosteric Modulators of Metabotropic Glutamate Receptors as Novel Therapeutics for Neuropsychiatric Disease
por: Luessen, Deborah J., et al.
Publicado: (2022) -
The metabotropic glutamate receptor 5 role on motor behavior involves specific neural substrates
por: Guimaraes, Isabella M, et al.
Publicado: (2015) -
Identification of Allosteric
Modulators of Metabotropic
Glutamate 7 Receptor Using Proteochemometric Modeling
por: Tresadern, Gary, et al.
Publicado: (2017)