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KRAS Mutations Are Associated with Shortened Survival in Patients with Epithelioid Malignant Pleural Mesothelioma

SIMPLE SUMMARY: Malignant pleural mesothelioma (MPM) is an aggressive tumor with implacable prognosis. It commonly harbors loss-of-function mutations in BAP1, NF2, CDKN2A and TP53, although their pathogenetic role is still uncertain since these genetic alterations, if isolated, do not cause MPM in m...

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Detalles Bibliográficos
Autores principales: Vannucchi, Margherita, Pennati, Veronica, Mencaroni, Clelia, Defraia, Chiara, Bardhi, Ledi, Castiglione, Francesca, Bellan, Cristiana, Comin, Camilla Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093256/
https://www.ncbi.nlm.nih.gov/pubmed/37046732
http://dx.doi.org/10.3390/cancers15072072