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Adefovir Dipivoxil as a Therapeutic Candidate for Medullary Thyroid Carcinoma: Targeting RET and STAT3 Proto-Oncogenes

SIMPLE SUMMARY: In this study, we employed a cell-based assay with a luciferase gene controlled by the RET promoter to identify small molecules that inhibit the transcription of the RET gene. The RET gene plays a role in the development of medullary thyroid carcinoma (MTC) as part of multiple endocr...

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Detalles Bibliográficos
Autores principales: Alqahtani, Tariq, Kumarasamy, Vishnu, Alghamdi, Sahar Saleh, Suliman, Rasha Saad, Bin Saleh, Khalid, Alrashed, Mohammed A., Aldhaeefi, Mohammed, Sun, Daekyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093259/
https://www.ncbi.nlm.nih.gov/pubmed/37046823
http://dx.doi.org/10.3390/cancers15072163