The TT Genotype of the KIAA1524 rs2278911 Polymorphism Is Associated with Poor Prognosis in Multiple Myeloma

Background: The KIAA1524 gene encodes an oncoprotein, CIP2A, which inhibits the phosphorylation of the Akt kinase B, stabilizes the c-Myc protein, and, through that, promotes cancerogenesis. An increase in CIP2A expression has been observed in numerous solid tumors and hematologic malignancies, incl...

Descripción completa

Detalles Bibliográficos
Autores principales: Szudy-Szczyrek, Aneta, Mlak, Radosław, Mazurek, Marcin, Krajka, Tomasz, Chocholska, Sylwia, Bitkowska, Paulina, Jutrzenka, Marta, Szczyrek, Michał, Homa-Mlak, Iwona, Krajka, Andrzej, Małecka-Massalska, Teresa, Hus, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093279/
https://www.ncbi.nlm.nih.gov/pubmed/37048102
http://dx.doi.org/10.3390/cells12071029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093279/
https://www.ncbi.nlm.nih.gov/pubmed/37048102
http://dx.doi.org/10.3390/cells12071029

Ejemplares similares