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The TT Genotype of the KIAA1524 rs2278911 Polymorphism Is Associated with Poor Prognosis in Multiple Myeloma

Background: The KIAA1524 gene encodes an oncoprotein, CIP2A, which inhibits the phosphorylation of the Akt kinase B, stabilizes the c-Myc protein, and, through that, promotes cancerogenesis. An increase in CIP2A expression has been observed in numerous solid tumors and hematologic malignancies, incl...

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Detalles Bibliográficos
Autores principales:	Szudy-Szczyrek, Aneta, Mlak, Radosław, Mazurek, Marcin, Krajka, Tomasz, Chocholska, Sylwia, Bitkowska, Paulina, Jutrzenka, Marta, Szczyrek, Michał, Homa-Mlak, Iwona, Krajka, Andrzej, Małecka-Massalska, Teresa, Hus, Marek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093279/ https://www.ncbi.nlm.nih.gov/pubmed/37048102 http://dx.doi.org/10.3390/cells12071029

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