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Immune Regulation by Cytosolic DNA Sensors in the Tumor Microenvironment

SIMPLE SUMMARY: Cytosolic DNA sensors (CDSs), expressed in various types of immune and tumor cells, recognize double-stranded DNA (dsDNA) in the cytoplasm. These molecules are activated after the dsDNA recognition and initiate a cascade of events that culminate in the activation of innate and acquir...

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Detalles Bibliográficos
Autor principal: Fukuda, Keitaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093344/
https://www.ncbi.nlm.nih.gov/pubmed/37046775
http://dx.doi.org/10.3390/cancers15072114