The αMSH-Dependent PI3K Pathway Supports Energy Metabolism, via Glucose Uptake, in Melanoma Cells

Stimulation of melanocytes and murine melanoma cells with αMSH plus the PI3K inhibitor LY294002 resulted in ROS increase, oxidative DNA damage, and pigment retention. We performed cellular and molecular biology assays (Western blot, FACS, immunofluorescence analysis, scratch assay) on murine and hum...

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Detalles Bibliográficos
Autores principales: Cardinali, Giorgia, Kovacs, Daniela, Mosca, Sarah, Bellei, Barbara, Flori, Enrica, Morrone, Aldo, Mileo, Anna Maria, Maresca, Vittoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093374/
https://www.ncbi.nlm.nih.gov/pubmed/37048170
http://dx.doi.org/10.3390/cells12071099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093374/
https://www.ncbi.nlm.nih.gov/pubmed/37048170
http://dx.doi.org/10.3390/cells12071099

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