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The αMSH-Dependent PI3K Pathway Supports Energy Metabolism, via Glucose Uptake, in Melanoma Cells
Stimulation of melanocytes and murine melanoma cells with αMSH plus the PI3K inhibitor LY294002 resulted in ROS increase, oxidative DNA damage, and pigment retention. We performed cellular and molecular biology assays (Western blot, FACS, immunofluorescence analysis, scratch assay) on murine and hum...
Autores principales: | Cardinali, Giorgia, Kovacs, Daniela, Mosca, Sarah, Bellei, Barbara, Flori, Enrica, Morrone, Aldo, Mileo, Anna Maria, Maresca, Vittoria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093374/ https://www.ncbi.nlm.nih.gov/pubmed/37048170 http://dx.doi.org/10.3390/cells12071099 |
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