miR-146a-5p Promotes Angiogenesis and Confers Trastuzumab Resistance in HER2+ Breast Cancer

SIMPLE SUMMARY: Resistance to anti-HER2+ therapy remains the main clinical challenge in the management of the HER2+ breast cancer subtype. The objective of our study was to analyze the involvement of microRNAs in the resistance to trastuzumab. We identified miR-146a-5p as the major dysregulated micr...

Descripción completa

Detalles Bibliográficos
Autores principales: Cabello, Paula, Torres-Ruiz, Sandra, Adam-Artigues, Anna, Forés-Martos, Jaume, Martínez, María Teresa, Hernando, Cristina, Zazo, Sandra, Madoz-Gúrpide, Juan, Rovira, Ana, Burgués, Octavio, Rojo, Federico, Albanell, Joan, Lluch, Ana, Bermejo, Begoña, Cejalvo, Juan Miguel, Eroles, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093389/
https://www.ncbi.nlm.nih.gov/pubmed/37046799
http://dx.doi.org/10.3390/cancers15072138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093389/
https://www.ncbi.nlm.nih.gov/pubmed/37046799
http://dx.doi.org/10.3390/cancers15072138

Ejemplares similares