Fatty Acid Excess Dysregulates CARF to Initiate the Development of Hepatic Steatosis

CARF (CDKN2AIP) regulates cellular fate in response to various stresses. However, its role in metabolic stress is unknown. We found that fatty livers from mice exhibit low CARF expression. Similarly, overloaded palmitate inhibited CARF expression in HepG2 cells, suggesting that excess fat-induced st...

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Detalles Bibliográficos
Autores principales: Hasan, Kamrul M., Parveen, Meher, Pena, Alondra, Bautista, Francisco, Rivera, Juan Carlos, Huerta, Roxana Ramirez, Martinez, Erica, Espinoza-Derout, Jorge, Sinha-Hikim, Amiya P., Friedman, Theodore C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093423/
https://www.ncbi.nlm.nih.gov/pubmed/37048142
http://dx.doi.org/10.3390/cells12071069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093423/
https://www.ncbi.nlm.nih.gov/pubmed/37048142
http://dx.doi.org/10.3390/cells12071069

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