α-Mangostin Promotes In Vitro and In Vivo Degradation of Androgen Receptor and AR-V7 Splice Variant in Prostate Cancer Cells

SIMPLE SUMMARY: Castration-resistant prostate cancer often develops in response to continued drug treatment and is characterized by mutations in the androgen receptor. Commonly used anti-androgen drugs are ineffective at targeting these cells; interestingly, our study evaluated a compound from Garci...

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Detalles Bibliográficos
Autores principales: Nauman, Mirielle C., Won, Jong Hoon, Petiwala, Sakina M., Vemu, Bhaskar, Lee, Hyun, Sverdlov, Maria, Johnson, Jeremy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093438/
https://www.ncbi.nlm.nih.gov/pubmed/37046780
http://dx.doi.org/10.3390/cancers15072118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093438/
https://www.ncbi.nlm.nih.gov/pubmed/37046780
http://dx.doi.org/10.3390/cancers15072118

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