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α-Mangostin Promotes In Vitro and In Vivo Degradation of Androgen Receptor and AR-V7 Splice Variant in Prostate Cancer Cells
SIMPLE SUMMARY: Castration-resistant prostate cancer often develops in response to continued drug treatment and is characterized by mutations in the androgen receptor. Commonly used anti-androgen drugs are ineffective at targeting these cells; interestingly, our study evaluated a compound from Garci...
Autores principales: | Nauman, Mirielle C., Won, Jong Hoon, Petiwala, Sakina M., Vemu, Bhaskar, Lee, Hyun, Sverdlov, Maria, Johnson, Jeremy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093438/ https://www.ncbi.nlm.nih.gov/pubmed/37046780 http://dx.doi.org/10.3390/cancers15072118 |
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