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New Findings: Hindlimb Unloading Causes Nucleocytoplasmic Ca(2+) Overload and DNA Damage in Skeletal Muscle

Disuse atrophy of skeletal muscle is associated with a severe imbalance in cellular Ca(2+) homeostasis and marked increase in nuclear apoptosis. Nuclear Ca(2+) is involved in the regulation of cellular Ca(2+) homeostasis. However, it remains unclear whether nuclear Ca(2+) levels change under skeleta...

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Detalles Bibliográficos
Autores principales: Yang, Huajian, Wang, Huiping, Pan, Fangyang, Guo, Yuxi, Cao, Liqi, Yan, Wenjing, Gao, Yunfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093444/
https://www.ncbi.nlm.nih.gov/pubmed/37048150
http://dx.doi.org/10.3390/cells12071077