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The Role of Mammalian STK38 in DNA Damage Response and Targeting for Radio-Sensitization

SIMPLE SUMMARY: DNA is constantly damaged by internal or external factors. Cells have evolved elaborate damage response mechanisms, namely, DNA damage response (DDR), to preserve genomic integrity. In eukaryotes, kinases play a central role in the DDR. Through a phosphorylation-dependent pathway, th...

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Detalles Bibliográficos
Autores principales: Fukasawa, Takemichi, Enomoto, Atsushi, Yoshizaki-Ogawa, Asako, Sato, Shinichi, Miyagawa, Kiyoshi, Yoshizaki, Ayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093458/
https://www.ncbi.nlm.nih.gov/pubmed/37046714
http://dx.doi.org/10.3390/cancers15072054