Phase I Study of a Combination of Fluvastatin and Celecoxib in Children with Relapsing/Refractory Low-Grade or High-Grade Glioma (FLUVABREX)

SIMPLE SUMMARY: This study tested the repurposing of two rationally selected, non-anticancer drugs as a way to address the need for less toxic therapeutic options in children with gliomas. The determined recommended phase II dose of fluvastatin in combination with celecoxib in children with gliomas...

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Detalles Bibliográficos
Autores principales: Leblond, Pierre, Tresch-Bruneel, Emmanuelle, Probst, Alicia, Néant, Nadège, Solas, Caroline, Sterin, Arthur, Boulanger, Thomas, Aerts, Isabelle, Faure-Conter, Cécile, Bertozzi, Anne-Isabelle, Chastagner, Pascal, Entz-Werlé, Natacha, De Carli, Emilie, Deley, Marie-Cécile Le, Bouche, Gauthier, André, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093481/
https://www.ncbi.nlm.nih.gov/pubmed/37046681
http://dx.doi.org/10.3390/cancers15072020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093481/
https://www.ncbi.nlm.nih.gov/pubmed/37046681
http://dx.doi.org/10.3390/cancers15072020

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