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S1P1 Threonine 236 Phosphorylation Mediates the Invasiveness of Triple-Negative Breast Cancer and Sensitivity to FTY720

Hyperactive sphingosine 1-phosphate (S1P) signaling is associated with a poor prognosis of triple-negative breast cancer (TNBC). Despite recent evidence that links the S1P receptor 1 (S1P1) to TNBC cell survival, its role in TNBC invasion and the underlying mechanisms remain elusive. Combining analy...

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Detalles Bibliográficos
Autores principales: Laroche, Fabrice J. F., Li, Sheng, Shen, Ning, Hwang, Soo Kyung, Nguyen, Gina, Yu, Wenling, Wong, Chen Khuan, Quinton, Ryan J., Berman, Jason N., Liu, Ching-Ti, Singh, Anurag, Ganem, Neil J., Thiagalingam, Sam, Feng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093541/
https://www.ncbi.nlm.nih.gov/pubmed/37048053
http://dx.doi.org/10.3390/cells12070980