Prevalence of a BRCA2 Pathogenic Variant in Hereditary-Breast-and-Ovarian-Cancer-Syndrome Families with Increased Risk of Pancreatic Cancer in a Restricted Italian Area

SIMPLE SUMMARY: Hereditary pathogenic/likely-pathogenic variants (PVs/LPVs) of BRCA1 and BRCA2 genes are the principal genetic cause of breast cancer (BC), ovarian cancer (OC), and other malignancies such as prostate (PrC) and pancreas (PC) carcinomas. The proportion of BRCA1 vs. BRCA2 is specific t...

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Detalles Bibliográficos
Autores principales: Zampiga, Valentina, Cangini, Ilaria, Bandini, Erika, Azzali, Irene, Ravegnani, Mila, Ravaioli, Alessandra, Mancini, Silvia, Tebaldi, Michela, Tedaldi, Gianluca, Pirini, Francesca, Veneroni, Luigi, Frassineti, Giovanni Luca, Falcini, Fabio, Danesi, Rita, Calistri, Daniele, Arcangeli, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093547/
https://www.ncbi.nlm.nih.gov/pubmed/37046793
http://dx.doi.org/10.3390/cancers15072132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093547/
https://www.ncbi.nlm.nih.gov/pubmed/37046793
http://dx.doi.org/10.3390/cancers15072132

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