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Glucagon Promotes Gluconeogenesis through the GCGR/PKA/CREB/PGC-1α Pathway in Hepatocytes of the Japanese Flounder Paralichthys olivaceus

In order to investigate the mechanism of glucagon regulation of gluconeogenesis, primary hepatocytes of the Japanese flounder (Paralichthys olivaceus) were incubated with synthesized glucagon, and methods based on inhibitors and gene overexpression were employed. The results indicated that glucagon...

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Detalles Bibliográficos
Autores principales: Yang, Mengxi, Pan, Mingzhu, Huang, Dong, Liu, Jiahuan, Guo, Yanlin, Liu, Yue, Zhang, Wenbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093564/
https://www.ncbi.nlm.nih.gov/pubmed/37048171
http://dx.doi.org/10.3390/cells12071098