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Sialofucosylation Enables Platelet Binding to Myeloma Cells via P-Selectin and Suppresses NK Cell-Mediated Cytotoxicity

SIMPLE SUMMARY: Platelet cloaking of tumor cells has been shown to play an important role in tumor metastasis and immune evasion. Multiple myeloma is a tumor of the plasma cells that colonizes different sites of the axial skeleton, including the skull. Herein, we show that specific carbohydrate stru...

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Detalles Bibliográficos
Autores principales: Natoni, Alessandro, Cerreto, Marina, De Propris, Maria Stefania, Petrucci, Maria Teresa, Fazio, Francesca, Intoppa, Stefania, Milani, Maria Laura, Kirkham-McCarthy, Lucy, Henderson, Robert, Swan, Dawn, Guarini, Anna, O’Dwyer, Michael, Foà, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093642/
https://www.ncbi.nlm.nih.gov/pubmed/37046814
http://dx.doi.org/10.3390/cancers15072154