Derivation and Preclinical Characterization of CYT-303, a Novel NKp46-NK Cell Engager Targeting GPC3

Glypican-3 (GPC3) is an oncofetal antigen that is highly expressed in multiple solid tumors, including hepatocellular carcinoma, and is barely expressed in adult normal tissues except the placenta. NKp46 activation receptor is expressed in all-natural killer (NK) cells, including tumor-infiltrating...

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Detalles Bibliográficos
Autores principales: Arulanandam, Antonio, Lin, Liang, Chang, Hao-Ming, Cerutti, Martine, Choblet, Sylvie, Gao, Peng, Rath, Armin, Bensussan, Armand, Kadouche, Jean, Teper, Daniel, Mandelboim, Ofer, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093649/
https://www.ncbi.nlm.nih.gov/pubmed/37048069
http://dx.doi.org/10.3390/cells12070996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093649/
https://www.ncbi.nlm.nih.gov/pubmed/37048069
http://dx.doi.org/10.3390/cells12070996

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