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Derivation and Preclinical Characterization of CYT-303, a Novel NKp46-NK Cell Engager Targeting GPC3
Glypican-3 (GPC3) is an oncofetal antigen that is highly expressed in multiple solid tumors, including hepatocellular carcinoma, and is barely expressed in adult normal tissues except the placenta. NKp46 activation receptor is expressed in all-natural killer (NK) cells, including tumor-infiltrating...
Autores principales: | Arulanandam, Antonio, Lin, Liang, Chang, Hao-Ming, Cerutti, Martine, Choblet, Sylvie, Gao, Peng, Rath, Armin, Bensussan, Armand, Kadouche, Jean, Teper, Daniel, Mandelboim, Ofer, Li, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093649/ https://www.ncbi.nlm.nih.gov/pubmed/37048069 http://dx.doi.org/10.3390/cells12070996 |
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