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5-Aza-2′-Deoxycytidine (5-Aza-dC, Decitabine) Inhibits Collagen Type I and III Expression in TGF-β1-Treated Equine Endometrial Fibroblasts

SIMPLE SUMMARY: Endometrosis is a major cause of infertility in mares and involves the excessive deposition of extracellular matrix in the mare’s endometrium, such as collagen and α smooth muscle actin (α-SMA). Collagen is formed by activated fibroblasts, which are mainly stimulated by transforming...

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Detalles Bibliográficos
Autores principales: Alpoim-Moreira, Joana, Szóstek-Mioduchowska, Anna, Słyszewska, Magda, Rebordão, Maria Rosa, Skarzynski, Dariusz J., Ferreira-Dias, Graça
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093662/
https://www.ncbi.nlm.nih.gov/pubmed/37048467
http://dx.doi.org/10.3390/ani13071212