Inhibition of LRRK2 Attenuates Depression-Related Symptoms in Mice with Moderate Traumatic Brain Injury

Moderate traumatic brain injury (mTBI) has been associated with emotional dysregulation such as loss of consciousness, post-traumatic amnesia and major depressive disorder. The gene Leucine-rich repeat kinase 2 (LRRK2) is involved in protein synthesis and degradation, apoptosis, inflammation and oxi...

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Detalles Bibliográficos
Autores principales: Filippone, Alessia, Cucinotta, Laura, Bova, Valentina, Lanza, Marika, Casili, Giovanna, Paterniti, Irene, Campolo, Michela, Cuzzocrea, Salvatore, Esposito, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093681/
https://www.ncbi.nlm.nih.gov/pubmed/37048114
http://dx.doi.org/10.3390/cells12071040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093681/
https://www.ncbi.nlm.nih.gov/pubmed/37048114
http://dx.doi.org/10.3390/cells12071040

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