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Inhibition of LRRK2 Attenuates Depression-Related Symptoms in Mice with Moderate Traumatic Brain Injury
Moderate traumatic brain injury (mTBI) has been associated with emotional dysregulation such as loss of consciousness, post-traumatic amnesia and major depressive disorder. The gene Leucine-rich repeat kinase 2 (LRRK2) is involved in protein synthesis and degradation, apoptosis, inflammation and oxi...
Autores principales: | Filippone, Alessia, Cucinotta, Laura, Bova, Valentina, Lanza, Marika, Casili, Giovanna, Paterniti, Irene, Campolo, Michela, Cuzzocrea, Salvatore, Esposito, Emanuela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093681/ https://www.ncbi.nlm.nih.gov/pubmed/37048114 http://dx.doi.org/10.3390/cells12071040 |
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