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Structural insights into acetylated histone ligand recognition by the BDP1 bromodomain of Plasmodium falciparum

Plasmodium falciparum requires a two-host system, moving between Anopheles mosquito and humans, to complete its life cycle. To overcome such dynamic growth conditions its histones undergo various post-translational modifications to regulate gene expression. The P. falciparum Bromodomain Protein 1 (P...

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Detalles Bibliográficos
Autores principales: Singh, Ajit Kumar, Phillips, Margaret, Alkrimi, Saleh, Tonelli, Marco, Boyson, Samuel P., Malone, Kiera L., Nix, Jay C., Glass, Karen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093686/
https://www.ncbi.nlm.nih.gov/pubmed/36328269
http://dx.doi.org/10.1016/j.ijbiomac.2022.10.247