High Glucose Activates Prolyl Hydroxylases and Disrupts HIF-α Signaling via the P53/TIGAR Pathway in Cardiomyocyte

The induction of hypoxia tolerance has emerged as a novel therapeutic strategy for the treatment of ischemic diseases. The disruption of hypoxic signaling by hyperglycemia has been shown to contribute to diabetic cardiomyopathy. In this study, we explored the potential molecular mechanisms by which...

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Detalles Bibliográficos
Autores principales: Chen, Jian-Xiong, Li, Lanfang, Cantrell, Aubrey C., Williams, Quinesha A., Zeng, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093703/
https://www.ncbi.nlm.nih.gov/pubmed/37048134
http://dx.doi.org/10.3390/cells12071060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093703/
https://www.ncbi.nlm.nih.gov/pubmed/37048134
http://dx.doi.org/10.3390/cells12071060

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